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Riehl Melanosis - StatPearls - NCBI Bookshelf. Facial melanoses affecting the face and neck region are of considerable concern to darker-skinned people. Although many facial melanoses, such as melasma, are well defined clinically, rendering them easy to diagnose, others have overlapping clinical morphology as well as histopathology.[1][2] Riehl melanosis (RM), commonly considered as a pigmented contact dermatitis (PCD), is one such .. Frequency of different types of facial melanoses referring to the .. Abnormalities of facial pigmentation, or facial melanoses, are a common presenting complaint in Nepal and are the result of a diverse range of conditions. The objective of this study was to determine the frequency, underlying cause and impact on quality of life of facial pigmentary disorders among patients visiting the Department of Dermatology and Venereology, Nepal Medical College and .. Riehl Melanosis - PubMed. Facial melanoses affecting the face and neck region are of considerable concern to darker-skinned people. Although many facial melanoses, such as melasma, are well defined clinically, rendering them easy to diagnose, others have overlapping clinical morphology as well as histopathology. Riehl melano …. Melanosis Definition & Meaning | Merriam-Webster Medical. noun. mel· a· no· sis ˌmel-ə-ˈnō-səs. plural melanoses -ˈnō-ˌsēz. : a condition characterized by abnormal deposition of melanins or sometimes other pigments in the tissues of the body.. A Study of Quality of Life in Patients with Facial Melanoses melanoses. Introduction. Appearance of face plays important role in self-perception.[] Also, skin plays a major role in social and sexual communication.[] Facial melanoses includes many overlapping clinical conditions and patients may experience severe consequences on self-concept.[1,3,4]Quality of life (QOL) means a feeling of joy and satisfaction with life and it has gained lot of importance.[]. Evaluation of Dermoscopic Features in Facial Melanosis with Wood Lamp . melanoses. Facial melanoses may also present as a result of ingestion of certain drugs like amiodarone, antimalarials, antipsychotics, chloramphenicol, clofazimine, pirfenidone and tetracycline . The diagnosis and differentiation of these conditions are based on history and clinical examination supplemented in some cases by Wood lamp and histopathological .. Melanoma - Wikipedia melanoses. Melanoma, also redundantly known as malignant melanoma, is a type of cancer that develops from the pigment-producing cells known as melanocytes. Melanomas typically occur in the skin, but may rarely occur in the mouth, intestines, or eye (uveal melanoma).In women, they most commonly occur on the legs, while in men, they most commonly occur on the back.. Idiopathic guttate hypomelanosis | DermNet melanoses. Women and patients with skin of colour are most likely to present for medical attention melanoses. Idiopathic guttate hypomelanosis becomes more common with age, affecting <50% in the fourth decade (31-40 years), 50-80% of people over 40 years of age, and >90% in the ninth decade (81-90 years) melanoses. It has been reported uncommonly in children and teens.. A Study of Quality of Life in Patients with Facial Melanoses melanoses. Context: Facial melanoses decreases the quality of life (QoL). Melasma is the commonest cause but there are various other etiologies for facial pigmentation melanoses. Aims: To study the clinical profile of patients with facial melanoses and the psychological burden in these patients. Settings and design: All patients having patchy or diffuse facial pigmentation attending the OPD in a tertiary care .. An overview of etiology and dermoscopic findings - Journal of Skin and .. Facial pigmentary disorder is a common condition in dark-skinned individual which causes significant psychological morbidity to the patients. Some of the well-defined causes of facial melanoses include melasma, Riehls melanosis, lichen planus pigmentosus, erythema dyschromicum perstans, and poikiloderma of Civatte. melanoses. Optimizing Q-switched lasers for melasma and acquired dermal melanoses. Acquired dermal melanoses are heterogenous entities with the common features of pigment incontinence and dermal melanophages resulting in greyish macular hyperpigmentation. This article reviews the current literature on laser toning in melasma and the role of the Q-switched Nd:YAG laser in stubborn pigmentary disorders such as lichen planus .. Melanosis Coli: Causes, Symptoms, and Treatment - WebMD. 3 min read melanoses. Melanosis coli is a medical condition caused by the release of a pigment molecule — called lipofuscin — into the mucus membranes of the large intestine (colon) melanoses. Melanosis coli isn .. Melanosis coli - Wikipedia. Prognosis. No adverse effects or consequences of melanosis coli have been identified. Relation to true melanoses. The condition is unrelated to true melanoses, such as Peutz-Jeghers syndrome and smokers melanosis. Peutz-Jeghers syndrome causes pigmentation of the skin and mucous surfaces with melanin, and polyps in the digestive tract melanoses. Non-colonic pseudomelanoses. Facial Melanosis | SpringerLink melanoses. Abstract. Facial melanosis is a common problem in pigmented skin melanoses. This is equally seen in both sexes even though majority is women who seek treatments. In middle-aged women, melasma is the commonest cause for facial melanosis while facial acanthosis in middle-aged men melanoses. Nasolabial and perioral hyperpigmentation is a well-recognized common . melanoses. Melanose Definition & Meaning - Merriam-Webster melanoses. melanose: [noun] a disease of the grapevine caused by a fungus (Septoria ampelina) that attacks the leaves causing them to fall.. Melanosis | definition of melanosis by Medical dictionary. melanosis. [ mel″ah-no´sis] 1. disordered melanin production, with darkening of the skin; called also melanism. 2. a disorder of pigment metabolism. melanosis co´li brown-black discoloration of the mucosa of the colon. melanosis i´ridis ( melanosis of the iris) abnormal pigmentation of the iris by infiltration of melanoblasts.. Dermal melanocytosis (previously known as Mongolian spot) melanoses. Dermal melanocytosis occurs when melanocytes fail to complete their migration from the neural crest to the basal layer of the epidermis. The melanocytes end their migration in the middle to lower dermis, where based on the Tyndall effect, their brown pigment gives the skins surface a blue-grey color. The Tyndall effect describes the .. A Brief History of Melanoma: From Mummies to Mutations. The earliest physical evidence of melanoma comes from the diffuse melanotic metastases found in the skeletons of Pre-Colombian mummies (radiocarbon dated to be ~2400 years old) from Chancay and Chingas in Peru ( 7 ). Between 1650-1760, the European medical literature, including the work of Highmore (1651), Bonet (1651), and Henrici and . melanoses

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. Mucosal melanosis - PubMed. All mucosal melanoses must be taken seriously by the physician, because it is usually not possible to exclude malignant melanoma on clinical inspection alone melanoses. A biopsy is always indicated. The labial melanotic macule and melanoacanthoma demonstrate histologic features strikingly different from those of melanoma. Although intraepithelial . melanoses. Oral Mucosal Melanosis | IntechOpen. In the mouth, melanin is produced by melanocytes residing in the basal cell layer of the oral epithelium. Melanin influences the colour of the oral mucosa and provides protection against reactive oxygen species and bacterial-derived enzymes and toxins and acts as a physical barrier to both microorganisms invading the oral epithelium and to other microenvironmental stressors

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Research Advances in the Treatment of Riehls Melanosis. For facial melanoses (FM), Riehls melanosis is one of the defined causes. 15 Application of topical depigmenting agents alone shows varying degrees of efficacy in the treatment of FM. Hydroquinone (HQ) may be the gold standard for FM, azelaic acid, kojic acid, retinoids, glycolic acid, tretinoin and topical corticosteroids are also used for .. Frequency of different types of facial melanoses referring to the .. Conclusion. Facial melanoses are a common presenting complaint and lead to substantial impacts on quality of life melanoses. Accurate diagnosis and management can prevent or treat many facial melanoses, including those that lead to substantial loss of quality of life, such as melasma with steroid induced rosacea-like dermatitis.. Idiopathic Guttate Hypomelanosis - StatPearls - NCBI Bookshelf. Idiopathic guttate hypomelanosis (IGH) is a benign, typically asymptomatic, leukodermic dermatosis of unclear etiology that is classically seen in elderly, fair-skinned individuals, and often goes unrecognized or undiagnosed. [1] Occasionally, IGH is aesthetically displeasing

However, it is not a dangerous process. Once present, lesions do not remit. Treatment is aimed at improving the .. Evaluation of Dermoscopic Features in Facial Melanosis with melanoses. - PubMed. Introduction: Facial melanosis is one of the most common reasons for which patients refer to a dermatologist in Nepal. Objectives: The objective of this study was to evaluate the dermoscopic findings of common facial melanoses and correlate them with findings from Wood lamp examination. Methods: This was a cross-sectional study conducted at the Department of Dermatology and Venereology, Nepal . melanoses. Acquired Dermal Macular Hyperpigmentation: An Update - PMC melanoses. Acquired dermal macular hyperpigmentation (ADMH) is an umbrella term that includes disorders, which are clinically characterized by small and large pigmented macules/patches and histopathologically show evidence of current or resolved interface dermatitis with pigment incontinence, without any clinically evident prior inflammatory skin lesions .

Conjunctival pigmented lesion: Clinicopathological analysis of 85 cases .. The remaining 5 eyes were diagnosed of having junctional nevus (one eye), benign epithelial melanoses (one eye), spindle cell nevus (one eye), and non-melanocytic lesions (2 eyes). Figure 1. Frequency of different types of facial melanoses referring to the .. Facial melanoses are a common presenting complaint and lead to substantial impacts on quality of life. Accurate diagnosis and management can prevent or treat many facial melanoses, including those that lead to substantial loss of quality of life, such as melasma with steroid induced rosacea-like der …. A Study of Quality of Life in Patients with Facial Melanoses. Abstract. Context: Facial melanoses decreases the quality of life (QoL)

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. Melasma is the commonest cause but there are various other etiologies for facial pigmentation. Aims: To study the clinical .. Mucosal Melanosis - ScienceDirect. Mucosal Melanosis. Melanosis is a term that has been used to describe pigmented macules and patches that develop on the mucosa of the lips, mouth, genitalia, and conjunctiva melanoses. These enigmatic conditions pursue a benign course but clinically may stimulate early malignant melanoma. Primary acquired melanosis of the conjunctiva is biologically .. Differential diagnosis of the conjunctival melanoses. The conjunctival melanoses are a group of diseases that share the common clinical findings of flat granular melanin-pigmentation of the conjunctival epithelium. Because differential diagnosis of these lesions is difficult, there is much confusion in the literature regarding taxonomy of these lesions

A histopathologic classification of benign .. 3 Ways to Treat Idiopathic Guttate Hypomelanosis - wikiHow. 1

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. Try weekly laser therapy treatments for about a month. If your dermatologist offers laser treatments, youll likely need to make quick visits each week for about a month melanoses. Spot treatments with the laser are usually painless, although you may experience some burning or redness in the treated areas. [3]. Optimizing Q-switched lasers for melasma and acquired dermal melanoses. Solar lentigo and other melanoses are bringing patients to the attention of physicians more and more often. The Q-switched 1064/532-nanometer (nm) laser is the gold standard device to treat these .. The pathogenesis of melasma and implications for treatment. Background. Melasma is a complex and poorly understood disorder, with high rates of treatment failure and recurrences. Objectives. We aimed to review the current knowledge of the pathogenesis of melasma and apply this knowledge to clinical implications on relevant therapeutic interventions.. Demodectic eruptions: More than you mite have imagined melanoses. By Warren R melanoses. Heymann, MD, FAAD April 26, 2023 Vol melanoses. 5, No. 17 melanoses. Despite the ongoing debate about the precise role of Demodex in the pathogenesis of multiple dermatoses (pityriasis folliculorum, papulopustular and granulomatous rosacea, perioral dermatitis, seborrheic dermatitis, blepharitis, and others), few would argue about the association of the mites with these entities, or that ivermectin .. Acquired dermal macular hyperpigmentation | DermNet. Acquired dermal macular hyperpigmentation, also called acquired macular pigmentation of unknown aetiology, comprises three conditions: Idiopathic eruptive macular hyperpigmentation [1,2]. The term acquired dermal macular hyperpigmentation is useful because the three conditions overlap. The subtypes may manifest in the same patient, and they . melanoses. Melanosis (Concept Id: C0025209) - National Center for Biotechnology . melanoses

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. Melanism; Melanoses: SNOMED CT: Melanosis (414662006); Melanism (239082002); Melanosis (48010006) Definition. Disorders of increased melanin pigmentation that develop without preceding inflammatory disease. [from MeSH] Term Hierarchy. GTR; MeSH;. Video image of genital melanosis provides strong evidence to support .. A man in his thirties was suspected of committing a sexual offense against a young girl. A video on his mobile telephone provided the only evidence melanoses. Photographs obtained from the video showed male genitalia in two views, with the penis in both views exhibiting .. Facial melanoses: Indian perspective | Request PDF - ResearchGate. Facial melanoses (FM) are a common presentation in Indian patients, causing cosmetic disfigurement with considerable psychological impact. Some of the well defined causes of FM include melasma .. Fractional CO2 laser and adjunctive therapies in skin . - ScienceDirect. Patients over 18 years of age with refractory melasma and Fitzpatrick skin type III to IV, who received ablative fractional CO₂ laser therapy alone or with laser toning and/or TXA from January 2010 to December 2020 were included in the study. Refractory melasma was defined as minimal or no response after 3 to 5 laser toning sessions and a TXA .. Dermoscopy of acquired pigmentary disorders: a comprehensive . - PubMed. This comprehensive review will summarize the growing literature on the use of dermoscopy for pigmentary disorders. A literature review was performed on PubMed dating from inception to October 2020. The following pigmentary disorders were included in this study: melasma, solar lentigines, poikiloderma of Civatte, exogenous ochronosis, lichen .. Periorbital Hyperpigmentation: A Comprehensive Review - PMC melanoses. Abstract. Periorbital hyperpigmentation is a commonly encountered condition. There is very little scientific data available on the clinical profile and pathogenesis of periorbital hyperpigmentation. Periorbital hyperpigmentation is caused by various exogenous and endogenous factors. The causative factors include genetic or heredity, excessive .. Penile Melanosis: Causes, Treatment and More - Daily Medical Health melanoses. Penile melanosis is a condition that affects men, causing the pigmentation of the skin on the penis to darken. This condition is relatively harmless and isnt usually a cause for concern melanoses. Symptoms of penile melanosis include a gradual darkening of the skin on the penis. This can happen due to a variety of factors, including age, genetics, and .

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. PDF Comparative Study on Combination of Microdermabrasion with 35% Glycolic .. Facial melanoses (FM) include a group of disorders with multifactorial etiology where diffuse or patchy hyperpigmentation present on the face and neck and is commoner in older woman. 1 Hyperpigmentary skin disorders may be broadly classified into two groups - Epidermal and dermal depending on the location of the pigment. Original Article Abstract melanoses. Cosmetics | Free Full-Text | Q-Switched Nd:YAG Laser to Manage . - MDPI melanoses. (1) Introduction: In cosmetic dermatology, benign hyperpigmentation is a prevalent issue

Solar lentigo and other melanoses are bringing patients to the attention of physicians more and more often. The Q-switched 1064/532-nanometer (nm) laser is the gold standard device to treat these conditions. A new generation of these machines, able to shorten pulse duration to hundreds of picoseconds, has .. Management of Iris Melanoma - American Academy of Ophthalmology. Whether to Biopsy. Iris melanoma is sometimes confirmed with fine-needle aspiration biopsy, though its not standard because of the associated risks. Dr. Shields finds it helpful for two reasons. First, cytology can show whether the cells are spindle, mixed, or epithelioid cell type. The latter is the most aggressive.. Feline iris melanosis - Veterinary Teaching Hospital. Feline iris melanosis. It is difficult to differentiate a benign freckle from a potentially malignant melanoma in the iris of a cat. Iris melanosis in cats is generally a benign change that should be monitored closely, while uveal melanoma is a malignant tumor, usually of the iris, that can be detrimental to the eye (causing inflammation and . melanoses. Differential diagnosis of the conjunctival melanoses - PubMed. The conjunctival melanoses are a group of diseases that share the common clinical findings of flat granular melanin-pigmentation of the conjunctival epithelium melanoses. Because differential diagnosis of these lesions is difficult, there is much confusion in the literature regarding taxonomy of these lesions. A histopathologic classification of benign . melanoses. An overview of etiology and dermoscopic findings - ResearchGate melanoses. Facial pigmentary disorder is a common condition in dark-skinned individual which causes significant psychological morbidity to the patients. Some of the well-defined causes of facial melanoses .. Atlas Entry - Ocular Melanocytosis - University of Iowa. Ocular melanocytosis (melanosis oculi) is a unilateral, congenital, pigmentary lesion that is a form of a blue nevus. The nevus is located in the deep episclera, sclera and uveal tract and can manifest clinically as iris heterochromia, patchy slate-gray or bluish discoloration of the sclera, and increased pigmentation of the ipsilateral fundus.. Melanosis intestini: case report - Diagnostic Pathology. Melanosis of the colon is not uncommon and has been associated with the ingestion of anthraceneline laxatives, although it can be observed in patients without such history [].Melanosis of the small intestine is an extremely rare finding with only a few cases described in the literature [1, 2, 4].Melanosis of the duodenum has been associated with several conditions such as chronic renal failure .. Oral mucosal melanoma - A systematic review - PubMed melanoses. Oral mucosal melanoma (OMM) is the subject of few studies, resulting in a lack of understanding. The aim of this study is to review the current literature on OMM. The term searched was "oral mucosal melanoma" between 01/01/2000 and 03/15/2021 in the PubMed Database (MEDLINE) melanoses. Patients presenting with OMM and treated in our center between .. Circumscribed dermal melanoses. Classification and histologic features . melanoses. Circumscribed dermal melanoses can be congenital or acquired and at times are nevoid in distribution. Bilateral nevus of Ota-like lesions and blue macules recently have been described in association with progressive systemic sclerosis. Macular amyloidosis and friction melanosis are also acquired dermal melanoses.. Circumscribed Dermal Melanoses: Classification and Histologic Features .. Circumscribed dermal melanoses are caused by either the presence of melanocytes in the dermis or the presence of melanin free in the dermis or within dermal melanophages. Some dermal melanoses are congenital or nevoid and others are acquired melanoses. Congenital or nevoid melanoses include Mongolian spots, blue nevus, nevus cell nevus, nevus of Ota . melanoses. Penile melanosis and lentiginosis - VisualDx. Synopsis. Genital melanosis and lentiginosis is a benign condition that is characterized by irregular pigmentation of the genital mucosa. Both females and males may be affected. In males, the glans penis is most commonly involved. Penile melanosis and lentiginosis may be seen in children and adults melanoses

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. When seen in children, it may be associated .. Video image of genital melanosis provides strong evidence to melanoses. - Springer. A man in his thirties was suspected of committing a sexual offense against a young girl. A video on his mobile telephone provided the only evidence. Photographs obtained from the video showed male genitalia in two views, with the penis in both views exhibiting unique pigmentation

We appraised this case with the cooperation of dermatologists, who diagnosed the pigmentation as male genital . melanoses. Differential diagnosis of melasma and hyperpigmentation. 1 INTRODUCTION. Melasma is an acquired hyperpigmentation disorder and is characterized by light-to-dark brown-colored irregular macules or patches on sun-exposed areas of skin, usually the face. 1 It is the most common cause of facial pigmentation and is a cutaneous disorder affecting all races with particular prominence in darker-skinned individuals. 2 Despite being a common condition with .. Idiopathic Guttate Hypomelanosis - American Osteopathic College . - AOCD melanoses. Idiopathic Guttate Hypomelanosis (IGH) is a benign and asymptomatic skin manifestation characterized as diffuse hypopigmented macules, or white spots. The size of the lesions varies from 1-10mm, but are most commonly 1-3 mm in diameter. It is most commonly seen in fair-skinned individuals and appears to be related to cumulative sun exposure .. Idiopathic Guttate Hypomelanosis (Leukopathia symmetrica progressiva). Idiopathic guttate hypomelanosis (IGH) is a common benign acquired condition that presents as small irregularly-shaped, well-defined hypopigmented porcelain white macules, predominantly on shins and forearm (Figure 1). The surface is smooth, without atrophy. Usually, the trunk and face are spared. Once present, lesions do not change in size.. Acquired hyperpigmentation disorders - UpToDate. Disorders of cutaneous discoloration comprise a large group of skin conditions characterized by an increase of chromophores of melanotic origin (hyperpigmentation) and/or an increase of nonmelanotic chromophores (hyperchromias) [ 1,2 ]. Hyperpigmentation is the darkening or increase in the natural color of the skin, usually due to an increased .. Optimizing Q-switched lasers for melasma and acquired dermal melanoses .. Dermal melanoses such as nevus of Ota and nevus of Ito have a predictable response to Q-switched Nd:YAG lasers with well-established protocols and melanoses. This article will focus on melasma. Though melasma can be epidermal, dermal or mixed, it is the dermal component that poses significant challenges to topical or standard therapy.. Clinical and Dermoscopic Features of Vulvar Melanosis Over the Last 20 .. Instead, a dermoscopic color assessment of the lesion was a useful and significant tool for diagnosing vulvar melanosis. The colors that were present in the vulvar melanoses of the patients were various shades of brown (100%) and black (60%) (Figure 3 C and D). Dermoscopically, these colors correspond to superficial structures, which correspond . melanoses

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. Ocular Melanosis - All About Vision. Melanocytes are the cells responsible for creating melanin.Melanin is what gives color to hair, eyes and skin. The more melanin is present in an area, the darker the color of that area. Ocular melanosis may appear as partial heterochromia, the presence of more than one color in the iris of the eye.It may also show up as gray or bluish spots on the sclera. melanoses. PDF A Study of Dermatoscopic Features in Facial Melanosis. dermatoscopic features in various facial melanoses. MATERIALS AND METHODS Source of data: All newly diagnosed, untreated patients with facial melanoses attending Dermatology OPD of Victoria hospital, BMC&RI, Bangalore. •••• Inclusion Criteria: Patients with facial melanosis of all age groups Patients who give consent. Nevos melanocíticos | Pedipedia - Enciclopédia Pediátrica Online. Definição Os nevos melanocíticos são lesões cutâneas pigmentares, congénitas ou adquiridas, constituídas por aglomerados (ninhos ou tecas) de células melanocíticas ou melanócitos, anteriormente também designadas como células névicas ou nevócitos. Os melanócitos derivam das células estaminais da crista neural e migram para a . melanoses. Curso Online Recursos Estéticos para Efélides e Melanoses - GoKursos .. O curso online Recursos Estéticos para Efélides e Melanoses aborda as manchas na pele do rosto que são uma das principais queixas de pacientes. O cursista ainda terá a oportunidade de conhecer como essas duas disfunções faciais acontecem, quais as características dessas manchas e como agem os principais tratamentos disponíveis no mercado atualmente. Esse curso é voltado para .. Lentigo Maligna: Keys to Dermoscopic Diagnosis - PubMed. Dermoscopy is a noninvasive technique that improves accuracy in the diagnosis of cutaneous lesions melanoses. The recognition and differential diagnosis of lentigo maligna (LM) and lentigo maligna melanoma (LMM) is challenging, especially in the early stages when there are no distinctive clinical features. Early diagnosis and appropriate treatment can . melanoses. Differential Diagnosis of Melasma in Brown Skin | SpringerLink. It is not usual and necessary to take a biopsy to prove that it is melasma

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. On the basis of circumscribed hyperpigmented macules or patches affecting the face, neck, and arms, almost symmetrically, the following are the most common differential diagnoses to consider: Postinflammatory hyperpigmentation melanoses. Exogenous ochronosis. melanoses. Inhibition of Melanosis in Whiteleg Shrimp. INTRODUCTION. Whiteleg shrimp (Litopenaeus vannamei) is one of the most widely cultured and consumed shrimp species because of its delicacy, accounting for 80% of the global shrimp production (Jescovitch et al., 2018).However, this high-value shrimp has a limited shelf life, in which melanosis (or black spot) formation during postmortem storage is problematic (Gonçalves and Oliveira, 2016 .. Q-switched Nd:YAG Laser Treatment for Acquired Bilateral Nevus . - PubMed. Background and objective: Acquired bilateral nevus of Ota-like maculae (ABNLM) is not an uncommon dermal melanosis in Asian people. It is known for its recalcitrance to conventional treatment. We proposed Q-switched Nd:YAG laser for the treatment of this entity.. PDF Melanosis (Blackspot) and Control in Shrimp in Louisiana - LSU. Melanosis (Blackspot) and Control in Shrimp in Louisiana Prepared by: Dr. Jon W. Bell, LSU AgCenter, Department of Food Science for La Sea Grant Louisiana Direct Program melanoses. Melanoses | definition of melanoses by Medical dictionary. melanosis: [ mel″ah-no´sis ] 1

disordered melanin production, with darkening of the skin; called also melanism . 2. a disorder of pigment metabolism. melanosis co´li brown-black discoloration of the mucosa of the colon. melanosis i´ridis ( melanosis of the iris ) abnormal pigmentation of the iris by infiltration of melanoblasts.. Consider melanoma, smokers melanosis, when diagnosing pigmented oral .. Smokers melanosis. In smokers melanosis, experts theorize that an unknown component in tobacco stimulates melanocytes to increase melanin production, Dr. Mirowski says. In a study of 908 Turkish army recruits, the rate of smokers melanosis was 27.5 percent in smokers versus 8.6 percent among recruits who had never smoked (Marakoğlu K ..